Variation of internal doses caused by differences in physical characteristics between the average Japanese and the ICRP's reference man which is based on the standard data of Caucasians in the dosimetric methodology in conformity to the 2007 Recommendations

Manabe, Kentaro; Sato, Kaoru; Takahashi, Fumiaki

Journal of Nuclear Science and Technology, 59(5), p.656 - 664, 2022/05

https://doi.org/10.1080/00223131.2021.1997663

It is known that internal doses depend on the physical characteristics of an evaluation subject. Internal dose coefficients provided by the International Commission on Radiological Protection (ICRP) are evaluated using the characteristics of the standard Caucasian. It is important to grasp the variations of doses due to the differences in characteristics between Japanese and Caucasian when the dose coefficients of ICRP are applied to Japanese. This study evaluated dose coefficients using specific absorbed fraction (SAF) data based on the average adult Japanese physique which was developed by modification of the existing Japanese SAF data with additional calculations to make the existing data fit to the current dosimetric methodology of ICRP and compared them to those provided by ICRP. As a result, the discrepancies in dose coefficients were smaller than plus or minus 10% in most intake conditions. However, some intake conditions indicated varieties over 40% due to the differences in organ masses, amount of adipose tissues around the thoracic cavity, and so on. This information is useful in application of ICRP's dose coefficients to population of which physical characteristics are different from those of Caucasian. Further, the Japanese SAF data is published as an appendix of this paper.

Japanese population dose from natural radiation

Omori, Yasutaka*; Hosoda, Masahiro*; Takahashi, Fumiaki; Sanada, Tetsuya*; Hirao, Shigekazu*; Ono, Koji*; Furukawa, Masahide*

Journal of Radiological Protection, 40(3), p.R99 - R140, 2020/09

https://doi.org/10.1088/1361-6498/ab73b1

UNSCEAR and the Nuclear Safety Research Association report the annual effective doses from cosmic rays, terrestrial radiation, inhalation and ingestion from natural sources. In this study, radiation doses from natural radiation sources in Japan were reviewed with the latest knowledge and data. Total annual effective dose from cosmic-ray exposure can be evaluated as 0.29 mSv. The annual effective dose from external exposure to terrestrial radiation for Japanese population can be evaluated as 0.33 mSv using the data of nationwide survey by the National Institute of Radiological Sciences. The Japan Chemical Analysis Center (JCAC) performed the nationwide radon survey using a unified method for radon measurements in indoor, outdoor and workplace. The annual effective dose for radon inhalation was estimated using a current dose conversion factor, and the values were estimated to be 0.50 mSv. The annual effective dose from thoron was reported as 0.09 mSv by UNSCEAR and then the annual effective dose from inhalation can be described as 0.59 mSv. According to the report of large scale survey of foodstuff by JCAC, the effective dose from main radionuclides due to dietary intake can be evaluated to be 0.99 mSv. Finally, Japanese population dose from natural radiation can be assessed as 2.2 mSv which is near to the world average value of 2.4 mSv.

Assessment of specific absorbed fractions for photons and electrons using average adult Japanese female phantom

Manabe, Kentaro; Sato, Kaoru; Takahashi, Fumiaki

JAEA-Data/Code 2016-013, 48 Pages, 2016/12

JAEA-Data-Code-2016-013.pdf:1.3MB
JAEA-Data-Code-2016-013-appendix(CD-ROM).zip:0.47MB

In the 2007 Recommendations of the International Commission on Radiological Protection (ICRP), an effective dose is defined as a sum of equivalent doses which are calculated by using male and female reference phantoms based on Caucasian physiological data and averaged over the sexes by tissue weighting factors. Specific absorbed fractions (SAFs), which are essential for internal dosimetry, depend on the body weight and organ masses of phantoms. Then, the dose coefficients, which are committed effective doses per unit intake of radionuclides, developed by ICRP on the basis of the 2007 Recommendations reflect the physical characteristics of Caucasians and are averaged over the sexes. Meanwhile, the physiques of adult Japanese are generally smaller than those of adult Caucasians, and organ masses are also different from each other. Knowledge of the influence of race differences on dose coefficients is important to apply the sex averaged dose coefficients of ICRP to the Japanese system of radiation protection. In this study, SAFs for 25 kinds of mono-energetic electrons and photons ranging from 10 keV to 10 MeV were calculated about the combinations of 67 source regions and 42 target organs using the average adult Japanese female phantom, JF-103, incorporated with a general purpose radiation transport code, MCNPX 2.6.0. The data of this report and the previously published data of JM-103 are applicable to evaluate sex-specific and sex-averaged dose coefficients reflecting the physical characteristics of the average adult Japanese for intakes of all radionuclides not to emit other than photons and electrons.

Numerical analysis of organ doses delivered during computed tomography examinations using Japanese adult phantoms with the WAZA-ARI dosimetry system

Takahashi, Fumiaki; Sato, Kaoru; Endo, Akira; Ono, Koji*; Ban, Nobuhiko*; Hasegawa, Takayuki*; Katsunuma, Yasushi*; Yoshitake, Takayasu*; Kai, Michiaki*

Health Physics, 109(2), p.104 - 112, 2015/08

https://doi.org/10.1097/HP.0000000000000299

A dosimetry system, named WAZA-ARI, is developed to assess accurately radiation doses to persons from Computed Tomography (CT) examination patients in Japan. Organ doses were prepared to application to dose calculations in WAZA-ARI by numerical analyses using average adult Japanese human models with the Particle and Heavy Ion Transport code System (PHITS). Experimental studies clarified the radiation configuration on the table for some multi-detector row CT (MDCT) devices. Then, a source model in PHITS could specifically take into account for emissions of X-ray in each MDCT device based on the experiment results. Numerical analyses with PHITS revealed a concordance of organ doses with human body size. The organ doses by the JM phantoms were compared with data obtained using previously developed systems. In addition, the dose calculation in WAZA-ARI were verified with previously reported results by realistic NUBAS phantoms and radiation dose measurement using a physical Japanese model. The results implied that analyses using the Japanese phantoms and PHITS including source models can appropriately give organ dose data with consideration of the MDCT device and physiques of typical Japanese adults.

Japanese adult male voxel phantom constructed on the basis of CT images

Sato, Kaoru; Noguchi, Hiroshi; Emoto, Yutaka*; Koga, Sukehiko*; Saito, Kimiaki

Radiation Protection Dosimetry, 123(3), p.337 - 344, 2007/02

https://doi.org/10.1093/rpd/ncl101

A Japanese adult male voxel (volume pixel) phantom (hereinafter referred to as the JM phantom) was constructed on the basis of CT images of a healthy Japanese adult male volunteer. Body characteristics of the JM phantom were compared with those of a voxelized MIRD5 type phantom and a Japanese adult male voxel phantom which was previously developed. The voxel size of the JM phantom is 0.980.981 mm. The shapes of organs of the JM phantom, even for small or complicated organs, such as thyroid and stomach, are more realistically reproduced as compared with the previous Japanese voxel phantom (voxel size: 0.980.9810 mm). Photon self-absorbed fractions for brain, kidneys, spleen, pancreas, thyroid and urinary bladder wall of JM were evaluated and were compared with those of the other phantoms. In consequence, it was suggested that the mass, shape and thickness of organs are important factors for the determination of self-absorbed fractions.

Evaluation of organ doses due to CT examination by using PHITS and adult Japanese phantoms

Sato, Kaoru; Takahashi, Fumiaki; Endo, Akira; Ono, Koji*; Hasegawa, Takayuki*; Katsunuma, Yasushi*; Yoshitake, Takayasu*; Ban, Nobuhiko*; Kai, Michiaki*

no journal, , 

The Japan Atomic Energy Agency are now developing WAZA-ARI for improvement of management of exposure doses due to CT examination under the joint research with the Oita University of Nursing and Health Sciences. The trial version of WAZA-ARI has been released to the public via the home page of the National Institute of Radiological Sciences for test operation. In trial version, users can perform dose assessment against average adult Japanese by using organ dose database based on the JM-103 (male) and JF-103 (female) phantoms with average body sizes of adult Japanese. To expand functions of WAZA-ARI to enables users to perform against adult patients with other body sizes, we developed the adult Japanese phantoms with small, large and extra-large body sizes by modifying JM-103 and JF-103. By dose analysis based on these phantoms, it was concluded that organ doses per current are strongly dependent on body sizes.

Development and utilization of Web-based open system for CT dose calculator, WAZA-ARIv2

Koba, Yusuke*; Nakada, Yoshihiro*; Matsumoto, Shinnosuke*; Akahane, Keiichi*; Ono, Koji*; Sato, Kaoru; Takahashi, Fumiaki; Endo, Akira; Shimada, Yoshiya*; Kai, Michiaki*

no journal, , 

While CT scan is useful for diagnosis, exposure dose derived from CT scan is relatively high. Therefore, it is important to manage patient doses and to prevent the excess exposures in young patients. JAEA developed the CT dose calculator, WAZA-ARIv2 under the collaboration research project with the National Institute of Radiological Sciences and the Oita University of Nursing and Health Sciences. In WAZA-ARIv2, users can accurately calculate exposure doses through the browser under consideration of patients information about sexes, ages (0y, 1y, 5y, 10y, 15y and adult) and fatness (small, large and extra-large body sizes). The functions of registration and database compilation of CT scan conditions and patient doses are newly added to a WAZA-ARIv2. Users can compare the distribution of patient doses in Japan with those in user's medical institution. Therefore, it will be expected that WAZA-ARIv2 can contribute the management and optimization of patients doses due to CT scan.

Calculating dose distribution from diagnostic CT depending on age and physique size of patients; Development of dose assessment web - system WAZA-ARI

Ono, Koji*; Koba, Yusuke*; Matsumoto, Shinnosuke*; Nakada, Yoshihiro*; Okuda, Yasuo*; Akahane, Keiichi*; Sato, Kaoru; Takahashi, Fumiaki; Yoshitake, Takayasu*; Hasegawa, Takayuki*; et al.

no journal, , 

In medical treatment, CT scan is useful diagnostic method. On the other hand, exposure doses derived from CT scans are dependent on body sizes of patients. Therefore, consideration of body sizes is essential for accurate dose assessment of individual patients. JAEA developed the CT dose calculator, WAZA-ARIv2 under the collaboration research project with the National Institute of Radiological Sciences and the Oita University of Nursing and Health Sciences. WAZA-ARIv2 enable users to accurately calculate exposure doses of patients with sexes, ages (0y, 1y, 5y, 10y, 15y and adult) and fatness (small, large and extra-large body sizes). In the future, we will be plans to add the dose calculation functions corresponding to the scan conditions at low tube voltage and multi-detector row (more 80) CT devices to WAZA-ARIv2. We reported the system and future plans of WAZA-ARIv2 corresponding to dose calculation of patients with various body sizes.

Evaluation of organ doses by using adult Japanese phantoms with various body sizes

Sato, Kaoru; Takahashi, Fumiaki

no journal, , 

Organ doses, which are basis of dose assessment in radiation protection, are derived from ICRP reference phantoms (Male: RCP-AM, Female: RCP-AF) with body physiques of standard Caucasian. In adult, Japanese body physiques are smaller than those of Caucasian. To study impact of application of organ doses of RCP-AM and RCP-AF to dose assessment of adult Japanese, we constructed Japanese male (JM-103) and female (JF-103) phantoms with body physiques of average adult Japanese. In addition, body physiques of adult Japanese have also wide distribution. Therefore, we newly constructed DJM (Male) and DJF (Female) with 8 body physiques by changing bust, chest, waist and hip of JM-103 and JF-103. Organ doses due to external photon irradiation of DJM and DJF were calculated, and were compared with those of RCP-AM and RCP-AF. In ISO geometry at 0.3 MeV and ROT geometry at 0.6 MeV, it was found that colon doses of DJM and DJF with body physiques, which are applicable to most adult Japanese, agreed with those of RCP-AM and RCP-AF within 10 %.

Analysis of effects of body sizes on organ doses due to CT examinations by using voxel phantoms

Sato, Kaoru; Takahashi, Fumiaki; Koba, Yusuke*; Ono, Koji*; Yoshitake, Takayasu*; Hasegawa, Takayuki*; Katsunuma, Yasushi*; Kasahara, Tetsuji*; Okuda, Yasuo*; Nakada, Yoshihiro*; et al.

no journal, , 

JAEA is now developing CT dose calculator named WAZA-ARIv2 in cooperation with the National Institute of Radiological Sciences. WAZA-ARIv2 has been opened to the public as full-dress uses on January 2015. WAZA-ARIv2 can perform dose assessment against 4 different body physiques by using the organ dose database, which were constructed on the basis of adult Japanese phantoms with 4 body sizes (-2, average, +2, +5). In this study, it was found that salivary gland doses are independent on BMI, whereas lung doses are dependent on BMI. The differences in the effects of BMI on absorbed doses between salivary glands and lungs might be caused by the difference in thickness of subcutaneous soft tissues between head and thorax.